CAMRD Project Number Principal Investigator Department Renewal Date Project Title
478 Dr. James Burke Neurology Feb-18 A Phase 2 Multiple Dose, Multicenter, Randomized,Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of ABBV-8E12 in Subjectswith Early Alzheimer's Disease
477 Dr. Patrick Hickey Neurology Feb-18 A Phase 1 Randomized, Double-Blinded, Placebo-Controlled Single-Ascending-Dose Study of the Safety, Tolerability, and Pharmacokinetics of BIIB054 in Healthy Subjects and Subjects with Early Parkinsonís Disease
476 Dr. Krantz Radiology Feb-18 Estimation of ICP changes following treatment of spontaneous intracranial hypotension using MRI
475 Dr. Moorman Ortho Feb-18 Moximed ATLAS Knee Spring Study
474 Dr. Driehuys Radiology Jan-18 Longitudinal MR Imaging of Pulmonary Function in Patients Receiving Thoracic Radiation Treatment
473 Dr. Driehuys Radiology Jan-18 Using MRI to Visualize Regional Therapy Response in Idiopathic Pulmonary Fibrosis
472 Dr. Provenzale Radiology Jan-18 Measurements of Reproducibility of DTI Metrics on MR scanners using a DTI Phantom
471 Dr. Kishnani Pediatrics Dec-17 An Open-label, Multicenter, Single-arm, Phase 4 Study of the Effect of Treatment with Velaglucerase alfa on Bone-related Pathology inTreatment-naÔve Patients with Type 1 Gaucher Disease
470 Dr. Lisberger Neurobiology May-17 Neural Control of Eye Movement
469 Dr. Driehuys Radiology Oct-17 Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects with Pulmonary Disease
468 Dr. Manal Abdelmalek Gastroenterology Nov-17 A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-0976 in Subjects with Nonalcoholic Steatohepatitis
467 Dr. Manal Abdelmalek Medicine/GI Sep-17 A Phase 2, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis
465 Dr. Andrew Muir Gastroenterology Aug-17 A PHASE 2, RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED,PARALLEL GROUP, MULTIPLE CENTER STUDY TO EVALUATETHESAFETY, TOLERABILITY, AND EFFICACY OF NGM282 ADMINISTERED FOR12 WEEKS IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS (PSC)
464 Dr. Jing Cai Rad Onc Aug-17 Magnetic Resonance Imaging (MRI) solely FOR liver stereotactic body radiation therapy (SBRT)
463 Dr. Kevin Hill Pediatric Cardio Aug-17 CHD Brain Connectome Study
462 Dr. Manal Abdelmalek Gastroenterology Aug-17 A Phase 2 Double-Blind, Randomized, Placebo controlled,Dose-finding Study to Evaluate the Safety, Tolerability and Efficacy of Volixibat Potassium, an Apical Sodium-Dependent Bile AcidTransporter Inhibitor (ASBTi) in Adults withNonalcoholic Steatohepatitis (NASH
461 Dr. Lou De Frate Orthopedics Jun-17 Lumbar Spine - Pilot Study
460 Dr. Chino Rad Onc Jun-17 Rad Onc
459 Dr. Abdelmalek Medicine Jun-17 A Phase 3, Double-Blind, Randomized, Long-Term, Placebo-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Obeticholic Acid in Subjects with Nonalcoholic Steatohepatitis.
458 Dr. Murat Rad Onc May-17 63935937MYF2001 RESEARCH (Janssen Study)
457 Dr. Bridget Koontz Rad Onc May-17 abi rt prostate
456 Dr. Soher Radiology Apr-17 Characterization of 2HG Protocol for Monitoring IDH1+ Subjects Using Single-Voxel MR Spectroscopy
455 †Lou DeFrate, MD Radiology Mar-17 In vivo measurement of patellar cartilage strain in response to running
454 Dr. Moylan-Bashir Medicine May-17 The Epigenetics of Pediatric Nonalcoholic Fatty Liver Disease and Fibrosis (SEEN: Study of Early Life, Epigenetics and NAFLD)
453 Murat Arcasoy, MD Oncology Mar-17 A Phase 2, Open-label, Translational Biology Study of Momelotinib in Transfusion-Dependent Subjects with Primary Myelofibrosis (PMF) or Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)
452 Dr. Priya Pediatrics-Medical Genetics Mar-17 Understanding cognitive and neurological pathologies in infantile Pompe disease
451 Grant E. Garrigues, MD Ortho Mar-17 Effect of exercise on glenohumeral cartilage mechanics
450 Dr. James Burke BrainTumor Clinic Oct-17 A Phase III, Randomized, Placebo-Controlled, Parallel-Group, Double-Blind Clinical Trial to Study the Efficacy and Safety of MK-8931 (SCH 900931) in Subjects with Amnestic Mild Cognitive Impairment Due to Alzheimerís Disease (Prodromal AD).
449 Dr. Janet Horton MD Rad Onc Sep-17 A PHASE II PREOPERATIVE SINGLE-FRACTION PARTIAL BREAST RADIOTHERAPY IN EARLY STAGE BREAST CANCER: ANALYSIS OF PATHOLOGIC RESPONSE
448 Dr. Katherine Peters BrainTumor Clinic Jul-17 A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion, Safety, Pharmacokinetic, Pharmacodynamic, and Clinical Activity Study of Orally Administered AG-881 in Patients with Advanced Solid Tumors, Including Gliomas, with an IDH1 and/or IDH2 Mutation
446 Manal Abdelmalek Gastroenterology Oct-17 A Phase IIb, double blind randomized, controlled clinical trial, to evaluate the efficacy and safety of two Aramchol doses versus placebo in patients with Non-Alcoholic Steatohepatitis (NASH
445 Burton Scott, MD Neurobiology Sep-17 A Phase 2, multi-center, randomized, double-blind, Placebo controlled study in subjects with late prodromal And early manifest Huntington disease (HD) to assess the safety, Tolerability, pharmacokinetics, and efficacy of VX15/2503
444 Dr. Kreissman Peds Sep-17 AALL1131 A Phase III Randomized Trial for Newly Diagnosed HR Pre-B ALL Testing Clofarbine
443 Jeffrey Crawford, MD Richard Reidel, MD Oncology Aug-17 Alliance A091105: A Phase III, Double Blind, Randomized, Placebo-Controlled Trial of Sorafenib in Desmoid Tumors or Aggressive Fibromatosis (DT/DF)
442 Murat Arcasoy, MD Oncology Oct-17 GS-US-352-1214 Memolotinib
441 Manal Abdelmalek Gastroenterology Jul-17 A Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Phase II Trial of JKB-121 for the Treatment of Nonalcoholic Steatohepatitis (NASH).†
440 Manal Abdelmalek Gastroenterology Jul-17 A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multiple Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamic Effects of BMS-986036 in Adults with Non-alcoholic Steatohepatitis
438 Richard Riedel, MD Oncology Oct-17 A Double-blind, randomized, Placebo-controlled Phase 3 Study of Orally Administered PLX3397 in Subjects with Pigmented Villonodular Synovitis or Giant Cell Tumor of the Tendon Sheath
437 Abdelmalek Manal MD Medicine /GI Jun-17 A Phase 2, Randomized, Double Blind, Placebo Controlled, Parallel Group, Multiple Center Study to Evaluate the Safety, Tolerability, and Efficacy of NGM282 Administered for 12 Weeks in Patients with Histologically Confirmed Nonalcoholic Steatohepatitis (NASH)†
435 Dr. Barboriak DCRU-BTC Nov-17 Phase I Single-Center, Dose Escalation Study of D2C7-IT Administered Intratumorally via Convection-Enhanced Delivery for Adult Patients with Recurrent Malignant Glioma
434 Dr. Edward Smith Pediatric Neurology Mar-17 A phase 2 randomized, double-blind,placebo-controlled, multiple ascending dose study to evaluate the safety, efficacy, pharmacokinetics and pharmacodynamics of PF-06252616 in ambulatory boys with Duchenne Muscular Dystrophy,
431 Dr. Toth Orthopedics Feb-17 The Use of the Miniopen Approach to Address Massive Rotator Cuff Tears with Alternative Matrix Supplementation
430 Dr. Manal Abdelmalek Medicine Oct-17 IMM-124E-2001: A phase II randomized, double-blind, placebo-controlled, 3-arm parallel group, multi-dose, multi-center study of IMM-124E (bovine colostrum) for patients with non-alcoholic steatohepatitis (NASH).
428 William Garrett MD Orthopedics Sep-17 Verifying the Effectiveness of the NUsurface System
427 Michaeil Harrison MD Med Onc Duke Cancer Sep-17 : EXTEND: Safety and Efficacy of EXercise Training in Men Receiving ENzalutamide in Combination with Conventional Androgen Deprivation Therapy for Hormone NaÔve Prostate Cancer
423 Claude Moorman, MD Ortho Aug-17 Prospective, Multi-Center, Pilot Study to Evaluate Symptom Relief in Patients with Medial Knee Osteoarthritis (OA) Treated with KineSpring Knee Implant for Load Reduction
422 Murat Arcasoy, MD Medicine/Oncology Mar-17 A Phase 3 Randomized Double-blind Active-controlled Study Evaluating Momelotinib vs. Ruxolitinib in Subjects with Primary Myelofibrosis or Post-Polycythemia Vera or Post-Essential Thrombocythemia Myelofibrosis
420 Alison Weidner OBGYN Mar-17 DEMAND
413 Brian J. Soher, PhD/Manal Abdemalek, MD Radiology Mar-17 Impact of fructose on Metabolism, Energy Homeostatis and MR biomarkers in NAFLD
412 Priya Kishnani, MD Pediatrics-Medical Genetics Mar-17 Natural history and biomarkers of disease in glycogen storage disease type III.
408 Joseph Mathew, MD Anesthesiology-Cardiac Division Mar-17 Blood Brain barrier Function After Cardiopulmonary Bypass†
407 Joseph Mathew, MD Anesthesiology Mar-17 Hydroxychloroquine and Cognitive Function after Cardiopulmonary Bypass†
406 Priya Kishnani, MD Pediatrics-Medical Genetics Mar-17 Role of Whole Body MRI as a Non-Invasive Technique for Monitoring Disease Progression and Treatment Efficacy in Pompe disease†
404 Lorel Del Mar Pena,MD.,Ph.D. Pediatrics-Medical Genetics Feb-17 An open-label, multicenter, multinational, ascending dose study of the safety, tolerability, pharmacokinetics, pharmacodynamics, and exploratory efficacy of repeated biweekly infusions of neoGAA in naÔve and alglucosidase alfa treated late-onset Pompe disease patients
403 James Burke, MD† DCRC Aug-17 TOMORROW Study (Takeda)
396 Charles E. spritzer, MD., Louis E. DeFrate, PhD Radiology/Orthopedics Renewal Pending The effect of mechanical stress, proteoglycan and collagen digesting enzymes on porcine explants as measured with T1-rho and T2 mapping
395 Steven A. Olson,MD †Orthopedics Mar-17 Assessment of Biomarkers Associated with joint Injury and Subsequent Post-Traumatic Arthritis
392 †Cecil Charles, PhD Radiology Oct-17 Human Lung Regional Ventilation Defect Severity measured by Fluorine-19 Gas MRI
389 Marc A. Sommer, PhD Biomedical Engineering Oct-17 Single Neuron Recording in Behaving Monkeys
379 Murat Arcasoy, MD Oncology Oct-17 An Open Label Assessment of Safety and Efficacy of Ruxolitinib (INCB018424) in Subjects with Primary Myelofibrosis, Post Essential Thrombocythemia-Myelofibrosis and Post Polycythemia Vera-Myelofibrosis Who Have Platelet Counts of 50 x 10^9/L to 100 x 10^9/L
376 †Lou DeFrate, MD Orthopedics† Renewal Pending Effect of Exercise on Cartilage Strain
365 Daniel Barboriak, MD Radiology Sep-17 Feasibility and reproducibility of advanced MRI methods in high grade gliomas after anti-angiogenic treatment
312 Jennifer M. Groh, PhD Center for Cognitive Neuroscience Apr-17 Anatomical scanning of rhesus macaque brain
306 Michael Platt, PhD Neurobiology Dec-17 Cortical and Subcortical Mechanisms of Eye Movement Control