| CAMRD Project Number |
Principal Investigator |
Project Title |
Renewal Date |
| 260 |
Michael J. Alexander, MD |
Evaluation of Neurovascular Microstent Grafts |
|
| 261 |
Michael D. De Bellis, MD |
A Research Study on Life Events and Childhood Brain Development |
|
| 262 |
Miguel A. Al. Nicolelis, MD.,PHD |
MRI-guided Sterotactic Localization for Electrode Placement in Non-human
Primates |
|
| 263 |
Kimberly Blackwell, MD |
Optimized Thrombin Inhibition (Refludan, Lepirudin (rdna Hirudin)
with and without weekly Docetaxel in Metastic Breast Cancer Patients |
|
| 264 |
Lin Sikich, MD |
Study of Human Brain in Youth with MRI and Spectroscopy |
|
| 265 |
Herbert Hurwitz, MD |
A Phase I, Open-Label, Multiple-Dose, Dose Escalation Study of GW786034 |
|
| 266 |
Frank Dunphy, MD |
Open Label, Phase I, Dose Escalation Study of Intralesional Injection
of Tetra-O-Methyl Nordihydroguaiaretic Acid (M4N) in Patients with Refactory
Malignant Tumors of the Head and Neck |
|
| 267 |
James Provenzale, MD |
Evaluation of Multiple Sclerosis Using Tensor DW Imaging and Multivoxel
Proton MR Spectroscopy |
|
| 268 |
K. Ranga R. Krishnan, MD |
Location of White Matter Hyperintensities and Alterations in White Matter
Tracts in Late Onset Depression (Duke Silvio Conte Center) |
1/2010 |
| 271 |
Michael D. De Bellis, MD |
Factors Influencing Childhood Brain Development |
|
|
272
|
Michael D. De Bellis, MD |
Adolescent Alcohol Abuse, PTSD and Hippocampal Development |
|
| 273 |
Dan Barboriak, MD |
Perfusion and Diffusion Tensor MR imaging of the Surgical Margin in Primary Cerebral Glioma |
|
| 276 |
Barrie Hurwitz, MD |
A Randomized, Rater-Blinded, Multicenter, Parallel-Group Study Comparing the Efficacy and Safety of Betaseron 250mcg Subcutaneously Every Other Day With Avonex 30mcg Intramuscularly Once A Week In Relapsing-remitting Multiple Sclerosis Patients Previously Treated with Avonex. (ABOVE) |
|
| 277 |
Laura Schanberg,MD |
A Multicenter, Randomized, Double-Blind Placebo-Controlled Study to test the Safety and Efficacy of Lipitor (atorvastatin) in Reducing the Progression of Carotid IMT in Early Childhood SLE. The Atherosclerosis Prevention in Pediatric Lupus Erythematosus (APPLE) Study |
3/2010 |
| 278 |
John Thomas, MD et. al. |
To assess the ability of Secretin stimulated MRCP to predict outcome in patients with pancreas divisum and pancreatitis, who will undergo minor papilla sphincterotomy. |
|
| 279 |
John Sampson, MD, Ph.D |
Pilot Imaging Study to Assess the Distribution of IL 13-PE38QQR Cytotoxin Infusions in Patients with Recurrent, Resectable, Supratentorial Malignant Glioma (IL-13PEI-105-R02 study). |
|
| 280 |
Nancy Major, MD |
Optimizing 3 Tesla MR Evaluation of the Acetabular Labrum |
|
| 281 |
H. Cecil Charles, Ph.D |
A Multi-Center, Double-blind, Placebo-controlled, Randomized, Parallel Group Evaluation of the Efficacy of a Flexible Dose of Lamotrigine versus Placebo As Add-On Therapy in Schizophrenia: Magnetic Resonance Spectroscopy (MRS) Substudy. |
|
| 282 |
Elmar M. Merkle, MD |
Breath-hold MRCP at 3T using a new dedicated body receiving coil - Comparison with state of the art MRCP at 1.5T. |
|
| 283 |
Priya Kishnani, MD
H.Cecil Charles, Ph.D
|
A Study of the progression of swallowing and breathing and the use of magnetic resonance spectroscopy to measure muscle glycogen content in children with Pompe disease |
|
| 284 |
H. Cecil Charles, Ph.D |
Optimization and Cross-Validation of MRI Sequences for Measuring Cartilage Volume |
|
| 285 |
Elmar Merkle, MD |
Parallel Imaging Acceleration of the VIBE Acquisition Technique in Hepatic MR Angiography: Potential Simultaneous Increase in Temporal Resolution and Contrast with Novel Gadolinium Regime |
|
| 286 |
John Sampson, MD, Ph.D |
Phase III Randomized Evaluation of Convection Enhanced Delivery of IL13-PE38QQR Compared to Gliadel® Wafer With Survival Endpoint in Glioblastoma Muliforme Patients At First Recurrence (PRECISE - IL13PE-301) |
|
| 287 |
Elmar Merkle, MD |
Comprehensive MR Approach in the Evaluation of Living Related Liver Donors: Comparison of Ultra High Field MRI at 3 Tesla with Contrast-Enhanced CT and ERCP |
|
| 288 |
Daniel George, MD |
A phase II open-label study of oral, continuous, once daily PTK787/ZK in subjects with VHL and HB |
|
| 289 |
Barrie Hurwitz, MD |
An international, randomized, multicenter, phase III study in patients with relapsing-remitting multiple sclerosis comparing over a treatment period of 104 weeks:
1. Double-blinded the safety, tolerability, and efficacy of Betaseron®/Betaferon® 250 µg (8 MIU) and Betaseron ®/Betaferon® 500µg (16 MIU), both given subcutaneously every other day, and
2. Rater-blinded the safety, tolerability, and efficacy of Betaseron®/Betaferon® 250 µg (8 MIU) s.c. every other day with Copaxone® 20 mg. s.c. once daily
BEYOND = Betaseron®/Betaferon® Efficacy Yielding Outcomes of a New Dose
|
|
| 290 |
Victoria Seewaldt, MD et. al. |
Does loss of retinoid receptor function promote breast cancer (RPFNA). |
8/2010 |
| 291 |
Lynne M. Hurwitz, MD |
Optimizing cardiac MR imaging on a 3T MRI system |
|
| 292 |
John Sampson, MD, Ph.D |
Phase I study of convection enhanced delivery (CED) of IL13-PE38QQR infusion after resection followed by radiation therapy with or without temozolomide in patients with newly diagnosed supratentorial malignant glioma |
|
| 293 |
Virginia Byers Kraus, MD, Ph.D
H. Cecil Charles, Ph.D
|
A Longitudinal Study of Osteoarthritis (OA) Disease Progression Measured by MRI, dGEMRIC, and Radiography. |
|
| 294 |
John L. Beyer, MD |
Bipolar Disorder in Late Life |
8/2010 |
| 295 |
Elmar Merkle, MD |
Evaluation of the Dielectric Cushion in Ultra High Field MRI of the Abdomen. |
|
| 296 |
David Steffens, MD; James MacFall, PhD |
Biomedical Informatics Research Network (BIRN) Reproducibility Study |
|
| 297 |
David A. Reardon, MD |
Dynamic Contrast Enhanced (DCE) and Diffusion Weighted Imaging (DWI) MRI in the Brain (2103) |
|
| 298 |
David A. Reardon, MD |
Dynamic Contrast Enhanced (DCE) and Diffusion Weighted Imaging (DWI) MRI in the Brain (2106) |
|
| 299 |
P. Murali Doraiswamy, MD |
Alzheimer's Disease Neuroimaging Initiative (ADNI) |
|
| 300 |
Barrie Hurwitz, MD |
A phase III, randomized, double-blind, three-arm, placebo-controlled, multi-center study to evaluate the safety and efficacy of oral cladribine in subjects with relapsing-remitting multiple sclerosis (RRMS) (Serono Protocol No. 25643) |
4/2010 |
| 301 |
Elmar Merkle, MD |
Phase 2 Study of CP-868,596 in Combination with Docetaxel and of Docetaxel alone in Patients with Stage IIIB or IV Non-Small Cell Lung Cancer, Preceded by a Phase IB Dose-Finding, safety and Tolerability study of the Combination in All Solid Tumor Types |
|
| 302 |
Elmar Merkle, MD; Herbert Hurwitz, MD |
Phase I Study of Every Other Week Anti-Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2) Monoclonal Antibody IMC-1121B in Patients with Advanced Solid Tumors Who Have Not Responded to Standard Therapy |
|
| 303 |
H. Cecil Charles, PhD; Virginia Kraus, PhD |
Development and Validation of glycosaminoglycan ("GAG") depletion mapping in osteoarthritis using delayed contrast enhanced MRI |
|
| 304 |
Mark Skeen, MD |
Multicenter, Randomized, Double-Blind, Placebo-controlled Study of Subcutaneous Toxaxin in Subjects with Clinically Isolated Syndrome or Relapsing-Remitting Multiple Sclerosis |
|
| 305 |
William E. Garrett, Jr., MD, PhD |
A Pilot Research Study On The Effects Of Intermittent Compression In Post-Surgical Knee Effusion |
|
| 306 |
Michael Platt,PhD |
Cortical and Subcortical Mechanisms Of Eye Movement Control |
8/2009 |
| 307 |
James A. Nunley, MD, Nancy Major, MD |
Infrapatellar Fat Pad: MRI Analysis In Correlation With Osteoarthritis of Knee Joint |
|
| 308 |
Nancy Major, MD |
MR Imaging of the Pelvis: Findings in Asymptomatic Collegiate Soccer Players |
|
| 309 |
Louis DeFrate, PhD |
Pig Knee Pilot Sudy for Meniscus Studies |
|
| 310 |
Ricki F. Goldstein, MD |
Neuroimaging and Neurodevelopmental Outcome: A Secondary to the Surfactant Positive Airway Pressure and Pulse Oximetry Trial (SUPPORT) |
|
| 311 |
Elmar Merkle, MD |
Diffusion Weighted Imaging of the Pancreas: Preliminary Experience in Healthy Volunteers |
|
| 312 |
Jennifer M. Groh,PhD |
Anatomical Scanning of Rhesus Macaque Brain |
8/2010 |
| 313 |
Louis DeFrate, PhD |
In Vivo Cartilage Contact Patterns in Patients with Meniscus Injury and Repair |
7/2010 |
| 314 |
Lee W. Jones, PhD |
Changes in Functional Status Across Therapy for Primary Glioma |
4/2010 |
| 315 |
Lisa M. Ho, MD |
Effects of Iodinated Contrast Media on Signal Intensity During Abdominal MR Imaging |
|
| 316 |
David Reardon, MD
|
Evaluation of Patients with Malignant Glioma Treated With Anti-Angiogenic Therapy Using Complimentary Magnetic Resonance Imaging Approaches |
|
| 317 |
Louis DeFrate, PhD |
In-vivo kinematics and contact of the ankle joint in patients with lateral ankle instability |
7/2009 |
| 318 |
Lee Cothran, MD |
Patellofemoral and tibiofemoral joint kinematics |
12/2009 |
| 319 |
Courtney Coursey, MD; Rendon Nelson, MD |
Pilot investigation of rate of injection and quantity of gadolinium injected using a phantom: What is the optimal injection rate and quantity? |
10/2009 |
| 320 |
Warren Taylor, MD |
Vascular Depression: Longitudinal Changes |
10/2009 |
| 321 |
Charles Spritzer, MD |
Alteration of cartilage contact points after ACL reconstruction |
10/2009 |
| 322 |
Charles Spritzer, MD |
Changes in Femoral/Tibial Cartilage Contact Points After Anterior Cruciate Ligament Reconstruction |
12/2009 |
| 323 |
William E. Kraus,MD (Co-investigators: R. Nelson, MD, Brian Soher, PhD, Cecil Charles, PhD) |
Magnetic Resonance Imaging (MRI) Sub-Study (STRRIDE) |
|
| 324 |
Kimberly Blackwell, MD |
Phase II Efficacy and Tolerability Study of RTA 744 in Breast Cancer Patients with Progression of Previously Irradiated Brain Metastases |
11/2009 |
| 325 |
Priya Kishnani, MD |
A Multicenter Open-Label Study of Gene-Activated Human Glucocerebrosidase (GA-GCB) Enzyme Replacement Therapy in Patients with Type 1 Gaucher Disease Previously Treated with Imiglucerase |
|
| 326 |
Priya Kishnani, MD |
A Multicenter, Randomized, Double-Blind, Parallel-Group Study of Gene-Activated® Human Glucocerebrosidase (GA-GCB) Enzyme Replacement Therapy Compared with Imiglucerase in Patients with Type I Gaucher Disease |
|
| 327 |
Nancy Major,MD |
Longitudinal 3-D 3T SPACE MRI and Articular Cartilage Lesions of the Knee |
1/2010 |
| 328 |
Warren D. Taylor, MD |
Genes and Alterations in Brain Structure and Function in Depression |
5/2010 |
| 329 |
Elmar M. Merkle, MD; Brian Soher, PhD |
Diagnosis and grading of liver fibrosis in a rat model: Using in vivo water-fat content discrimination and time-resolved diffusion-weighted MR imaging after fructose stimulation |
2/2009 |
| 330 |
Sujata Ghate, MD |
MRI Artifact Evaluation of Marking Clips in a Breast Phantom |
9/2010 |
| 331 |
M. Tariq Bratti, MD |
A two-arm, ramdomized, double-blind, placebo-controlled, multicenter Phase II study to evaluate safety and tolerability and to explore the neuroprotective effect of atacicept as assessed by Optical Coherence Tomography (OCT) in subjects with Optic Neuritis (ON) as Clinically Isolated Syndrome (CIS) over a 36 week treatment course. |
7/2009 |
| 332 |
Priya Kishnani, MD |
An open-label, multicenter study to evaluate the safety, tolerability, pharmacodynamics, and pharmacokinetics of three dosing regimens of oral AT2220 in patients with Pompe disease. |
9/2009 |
| 333 |
David A. Reardon, MD |
BRAD-301: A Phase III Randomized Study of Neuradiab in Combination with External Beam Radiation and Temozolomide Versus External Beam Radiation and Temozolomide in Patients with Newly Diagnosed Glioblastoma Multiforme. |
10/2009 |
| 334 |
Carmelo Graffagnino, MD |
Minimally Invasive Surgery plus rt-PA for ICH Evacuation (MISTIE). |
10/2009 |
| 335 |
Danielle Lemuth,MD |
Interobserver Variability of Breast MR Spectroscopy. |
12/2009 |
| 336 |
Ashley Hawkins, MD |
Magnetic Resonance Spectroscopy and Diffusion Weighted Imaging for Detection of Early Response to Neoadjuvant Breast Chemotherapy. |
2/2010 |
| 337 |
Chuck Spritzer,MD |
Knee Kinmatics in Normal Subjects. |
2/2010 |
| 338 |
Michael Paldino, MD |
Reproducibility of Advanced MRI Methods in Patients with Primary Brain Tumors. |
3/2010 |
| 339 |
H. Cecil Charles, PhD |
Evaluation of Regional Ventilation in Normal Subjects and Subjects with Airway and Lung Disorders Using 19F Magnetic Resonance Imaging of Inert Perfluorinated Gases mixed with Oxygen (SF6, and PFP): A Phase 1 Study |
4/2010 |
| 340 |
Manal Abdelmalek, MD |
Quantification of Hepatic Fat Content Using Various MR Techniques. |
4/2010 |
| 341 |
Chuck Spritzer,MD |
Electromyostimulation in Healthy Volunteers. |
4/2010 |
| 342 |
Annick Desjardins, MD |
A Phase III, Randomized, Parallel Group, Multi-Centre Study in Recurrent Glioblastoma Patients to Compare the Efficacy of Cediranib [Recentin (TM), AZD2171] Monotherapy and the Combination of Cediranib with Lomustine to the Efficacy of Lomustine Alone. |
5/2010 |
| 343 |
Chuck Spritzer,MD |
Wrist Kinematics in Patients with Triangular Fibrocartilage Complex Tears. |
8/2010 |
| 344 |
Priya Kishnani,MD |
GZGD02507(ENGAGE): A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study Confirming the Efficacy and Safety of Genz-112638 in Patients with Gaucher Disease Type I. |
9/2010 |
| 345 |
Priya Kishnani,MD |
GZGD02607: A phase 3, Randomized, Multi-Center, Multi-National, Open-Label, Active Comparator Study to Evaluate the Efficacy and Safety of Genz-112638 in Patients with Gaucher Disease Type I who have been stabilized on Cerezyme. |
9/2010 |
| 346 |
Charles Kim, MD; Elmar Merkle, MD |
Prospective Evaluation of Non-Contrast MR Angiography of the Central Veins of the Chest. |
11/2010 |
| 347 |
Chuck Spritzer, MD |
In-Vivo Cartilage Deformation after Acetabular Labral Tear. |
11/2010 |
| 348 |
Murat O. Arcasoy, MD |
A Randomized, Double-Blind, Placebo-Controlled Study of JAK2 Inhibitor INCB018424 Tablets Administered Orally to Subjects with Primary Myelofibrosis (PMF) and Post Polycythemia Vera-Myelofibrosis or Post Essential Throbocythemia Myelofibrosis (Post-PV/ET MF) |
11/2010 |
| 349 |
Priya Kishnani, MD |
An Open-Label Expanded Access Trial of Plant Cell Expressed Recombinant Human Glucocerebrosidase (prGCD) in Patients with Gaucher Disease Who Require Enzyme Replacement Therapy |
11/2010 |